3 ms·

The standard treatment for H pylori is two antibiotics For 14 days.

by nashashmi 2y ago

thaumasiotes 2y ago
Well, the standard treatment is to ignore it. It's present in over a third of people and causes no symptoms.
- throwuxiytayq 2y ago
  20% of patients have symptoms and all carriers are at risk of developing cancer.
  - thaumasiotes 2y ago
    All non-carriers are also at risk of developing cancer. How much worse does H. pylori make that situation? Combining some reports from various places: > Infection of the stomach with H. pylori is not the cause of illness itself; over half of the global population is infected but most are asymptomatic. > Infection with H. pylori is responsible for around 89 per cent of all gastric cancers ( https://en.wikipedia.org/wiki/Helicobacter_pylori https://en.wikipedia.org/wiki/Helicobacter_pylori ) > 770,000 deaths of gastric cancer were estimated in 2020 ( https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00134-1/fulltext https://www.thelancet.com/journals/eclinm/article/PIIS2589-5... ) 58 million deaths worldwide in 2019 according to https://ourworldindata.org/grapher/number-of-deaths-per-year https://ourworldindata.org/grapher/number-of-deaths-per-year ; I picked 2019 instead of 2020 because 2020 features a spike in deaths for reasons that I'm assuming are unrelated to cancer. That puts gastric cancer deaths from H. pylori at just under 1.2% of all deaths, which frankly seems ridiculously high. https://seer.cancer.gov/statfacts/html/stomach.html https://seer.cancer.gov/statfacts/html/stomach.html suggests that stomach cancer is 1.8% of all cancer deaths (in the USA), which is perfectly compatible with the above statistics as long as cancer is the cause of 67% of all deaths. The death rate from stomach cancer is about 3 per 100,000 people (in the USA). The overall death rate, per https://stacks.cdc.gov/view/cdc/79486 https://stacks.cdc.gov/view/cdc/79486, is 864 per 100,000, putting stomach cancer at 0.3% of all deaths. In the USA. Is this actually something we worry about? Most people are infected; virtually no one gets cancer.
  - bongodongobob 2y ago
    [flagged]
- nashashmi 2y ago
  No symptoms? Excess passing of gas and acid reflux and GERD. They might be a series of ignored symptoms. Not a lack of symptoms. PSA: get yourself checked. The treatment will literally destroy all your gut bacteria and renew your stomach to a healthier state. It will be a miserable two weeks though.
  - thaumasiotes 2y ago
    No, no symptoms.
    - itishappy 2y ago
      > Infection with H. pylori is responsible for around 89% of all gastric cancers, and is linked to the development of 5.5% of all cases of cancer worldwide. Although the data varies between different countries, overall about 1% to 3% of people infected with Helicobacter pylori develop gastric cancer in their lifetime compared to 0.13% of individuals who have had no H. pylori infection. H. pylori-induced gastric cancer is the third highest cause of worldwide cancer mortality as of 2018. Because of the usual lack of symptoms, when gastric cancer is finally diagnosed it is often fairly advanced. More than half of gastric cancer patients have lymph node metastasis when they are initially diagnosed. I've got symptoms, but this would scare me even if I didn't.

The standard treatment for H pylori is two antibiotics For 14 days.

thaumasiotes 2y ago

Well, the standard treatment is to ignore it. It's present in over a third of people and causes no symptoms.

throwuxiytayq 2y ago
20% of patients have symptoms and all carriers are at risk of developing cancer.
- thaumasiotes 2y ago
  All non-carriers are also at risk of developing cancer. How much worse does H. pylori make that situation? Combining some reports from various places: > Infection of the stomach with H. pylori is not the cause of illness itself; over half of the global population is infected but most are asymptomatic. > Infection with H. pylori is responsible for around 89 per cent of all gastric cancers ( https://en.wikipedia.org/wiki/Helicobacter_pylori https://en.wikipedia.org/wiki/Helicobacter_pylori ) > 770,000 deaths of gastric cancer were estimated in 2020 ( https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00134-1/fulltext https://www.thelancet.com/journals/eclinm/article/PIIS2589-5... ) 58 million deaths worldwide in 2019 according to https://ourworldindata.org/grapher/number-of-deaths-per-year https://ourworldindata.org/grapher/number-of-deaths-per-year ; I picked 2019 instead of 2020 because 2020 features a spike in deaths for reasons that I'm assuming are unrelated to cancer. That puts gastric cancer deaths from H. pylori at just under 1.2% of all deaths, which frankly seems ridiculously high. https://seer.cancer.gov/statfacts/html/stomach.html https://seer.cancer.gov/statfacts/html/stomach.html suggests that stomach cancer is 1.8% of all cancer deaths (in the USA), which is perfectly compatible with the above statistics as long as cancer is the cause of 67% of all deaths. The death rate from stomach cancer is about 3 per 100,000 people (in the USA). The overall death rate, per https://stacks.cdc.gov/view/cdc/79486 https://stacks.cdc.gov/view/cdc/79486, is 864 per 100,000, putting stomach cancer at 0.3% of all deaths. In the USA. Is this actually something we worry about? Most people are infected; virtually no one gets cancer.
- bongodongobob 2y ago
  [flagged]
nashashmi 2y ago
No symptoms? Excess passing of gas and acid reflux and GERD. They might be a series of ignored symptoms. Not a lack of symptoms. PSA: get yourself checked. The treatment will literally destroy all your gut bacteria and renew your stomach to a healthier state. It will be a miserable two weeks though.
- thaumasiotes 2y ago
  No, no symptoms.
  - itishappy 2y ago
    > Infection with H. pylori is responsible for around 89% of all gastric cancers, and is linked to the development of 5.5% of all cases of cancer worldwide. Although the data varies between different countries, overall about 1% to 3% of people infected with Helicobacter pylori develop gastric cancer in their lifetime compared to 0.13% of individuals who have had no H. pylori infection. H. pylori-induced gastric cancer is the third highest cause of worldwide cancer mortality as of 2018. Because of the usual lack of symptoms, when gastric cancer is finally diagnosed it is often fairly advanced. More than half of gastric cancer patients have lymph node metastasis when they are initially diagnosed. I've got symptoms, but this would scare me even if I didn't.