IME, PyPy can get up to 100x faster for many use cases. Most of my Python scripts have a lot of pure-Python code manipulating ints, strs, dicts, etc. (wrangling

IME, PyPy can get up to 100x faster for many use cases. Most of my Python scripts have a lot of pure-Python code manipulating ints, strs, dicts, etc. (wrangling data between formats and/or doing basic processing), and switching from CPython to PyPy often turns the execution time from minutes into seconds. You'll likely get much less of a speedup if your program is already optimized around CPython's slowness, e.g., by calling out to libraries like numpy as much as possible. But PyPy lets my simple scripts punch above their weight without any extra circumlocutions.