3 ms·
Calorie restriction is a well-studied (though not terribly healthy) way to slow aging. It's likely these drugs are just making it easier for people.
by smt88 2y ago
Calorie restriction is a well-studied (though not terribly healthy) way to slow aging. It's likely these drugs are just making it easier for people.
- kiba 2y agoCalories restriction worked in a wide variety of species but was inconclusive in monkeys and was never proven in humans.
- smt88 2y agoI'm not sure what standard you're using for "proven," but there are a lot of studies showing results similar to this one: https://www.publichealth.columbia.edu/news/calorie-restriction-slows-pace-aging-healthy-adults https://www.publichealth.columbia.edu/news/calorie-restricti... There don't seem to be any huge, long-term studies, but here is a review of what's available as of a few years ago: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468870/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7468870/
- woleium 2y agoSee Roy Walford et al out of UCLA on the CRON diet. Its not a nice way to live, but it seems to be safe and healthy.
- smt88 2y agoI'll have to look into it more, but from what I've seen, it seemed that people had to restrict calories so much that their immune system was underactive (which may be a large part of why it works).
- woleium 2y agoInteresting, i last looked at this over 10 years ago, i assume this came to light more recently than that.
- rendaw 2y agoI thought calorie restriction was another order of magnitude, beyond "normal" weight. But I guess if obesity was causing accelerated ageing, you could say not being obese is delaying ageing.
- smt88 2y agoIt varies from study to study, but generally what I've seen for anti-aging is ~1,000 calories per day or less. I've seen it as low as 500.