It really depends on what you need to do with the data, but in most cases Python could do this pretty easily with csv.reader (with a \t delimiter for TSV) or xm

It really depends on what you need to do with the data, but in most cases Python could do this pretty easily with csv.reader (with a \t delimiter for TSV) or xml.etree.ElementTree.iterparse (for XML) in streaming fashion such that you're not loading the whole file at once.