Weechat can also be used in a client/server architecture. It can run headless and expose a relay protocol (full weechat control and state) and/or an irc server

Weechat can also be used in a client/server architecture. It can run headless and expose a relay protocol (full weechat control and state) and/or an irc server (traditional bouncer). Though, ironically, there are no CLI clients for its relay protocol, only for desktop/web/android.