2 ms·
Whether this is valid in humans likely depends on the Alzeimers mouse model. Some of the mouse models are really good because we can inject the mouse with somet
by PaulKeeble 2y ago
Whether this is valid in humans likely depends on the Alzeimers mouse model. Some of the mouse models are really good because we can inject the mouse with something humans get and they suffer a similar fate. But for a lot of these complex diseases the analogues can be very unrepresentative or require genetically modified mice and they tend to translate less well.
"researchers used mice that were genetically modified to have symptoms of Alzheimer’s disease" is what I am concerned about. I remain hopeful it translates across and IDO1 has been implicated in a bunch of conditions so such a drug might find some other uses.