3 ms·

At the bottom of the page, in related stories, there's a Hampshire man who seemed to age extraordinarily between 31 March 2020 (officially recognised as world's

by OJFord 2y ago

At the bottom of the page, in related stories, there's a Hampshire man who seemed to age extraordinarily between 31 March 2020 (officially recognised as world's oldest man) and 28 May (died). (And not in a particularly weak/sick sort of way, just looks about thirty years older, if the same man at all.) --- I think Ms Morera's the long-liver I've previously read suggesting something amusing like 'plenty of olive oil and a glass of red wine every evening' as key to it, but searching for that now all I can find is the present holder of 'world's oldest man', Mr Tinniswood, suggesting 'fish & chips on a Friday & regular walks'. (https://www.independent.co.uk/life-style/oldest-man-long-life-tips-secret-old-age-b2525216.html https://www.independent.co.uk/life-style/oldest-man-long-lif...)

lawlessone 2y ago
>a glass of red wine every evening' They often have stories like this. Glass of wine. Shot of whiskey. Cigars etc. Sometimes i wonder if it is hormesis. Other times I think it's probably just genes and luck and that alcohol/cigar etc had very little influence.
- rajnathani 2y ago
  Hormesis is a pretty interesting thing (thanks, as TIL). Just a thought, the tiny amount of ethanol in fermented dairy products like cultured buttermilk, yogurt, and kefir, could maybe play a tiny factor in some of its health benefits? The logic here is that for a micronutrient such as Vitamin A that all it takes is 1/1000th of a gram on a daily basis for health benefits (the same goes for many other vitamins' RDA for humans). As an aside, there is an interesting part of the ethanol section in the Wikipedia entry [0] on hormesis: > In 2012, researchers at UCLA found that tiny amounts (1 mM, or 0.005%) of ethanol doubled the lifespan of Caenorhabditis elegans, a roundworm frequently used in biological studies, that were starved of other nutrients. Higher doses of 0.4% provided no longevity benefit.[22] However, worms exposed to 0.005% did not develop normally (their development was arrested). The authors argue that the worms were using ethanol as an alternative energy source in the absence of other nutrition, or had initiated a stress response. They did not test the effect of ethanol on worms fed a normal diet. [0] https://en.wikipedia.org/wiki/Hormesis https://en.wikipedia.org/wiki/Hormesis

by OJFord 2y ago

lawlessone 2y ago

>a glass of red wine every evening' They often have stories like this. Glass of wine. Shot of whiskey. Cigars etc. Sometimes i wonder if it is hormesis. Other times I think it's probably just genes and luck and that alcohol/cigar etc had very little influence.

rajnathani 2y ago
Hormesis is a pretty interesting thing (thanks, as TIL). Just a thought, the tiny amount of ethanol in fermented dairy products like cultured buttermilk, yogurt, and kefir, could maybe play a tiny factor in some of its health benefits? The logic here is that for a micronutrient such as Vitamin A that all it takes is 1/1000th of a gram on a daily basis for health benefits (the same goes for many other vitamins' RDA for humans). As an aside, there is an interesting part of the ethanol section in the Wikipedia entry [0] on hormesis: > In 2012, researchers at UCLA found that tiny amounts (1 mM, or 0.005%) of ethanol doubled the lifespan of Caenorhabditis elegans, a roundworm frequently used in biological studies, that were starved of other nutrients. Higher doses of 0.4% provided no longevity benefit.[22] However, worms exposed to 0.005% did not develop normally (their development was arrested). The authors argue that the worms were using ethanol as an alternative energy source in the absence of other nutrition, or had initiated a stress response. They did not test the effect of ethanol on worms fed a normal diet. [0] https://en.wikipedia.org/wiki/Hormesis https://en.wikipedia.org/wiki/Hormesis