In the most extreme acute situations I have broken down to tears purely from over-stimulation from socializing. Specifically when attending conferences for work

In the most extreme acute situations I have broken down to tears purely from over-stimulation from socializing. Specifically when attending conferences for work. (I am an introvert). After a day of intense socializing I will go back to a hotel room and cry, while other people go to after parties. As far as depression, drugs, etc. I haven't been under this pressure chronically so I can't speak from personal experience. That said, I suspect that for introverts in even the most extreme chronic social pressures it would be more feasible for them to escape to some quiet place to recharge, than it would be for an extrovert who has no social connection living in isolation to find sufficient connection to recharge. In theory, it's far more practical to manifest solitude than it is to manifest a party.