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One important note with mpox is that there are two distinct lineages of the virus at play: the outbreak in the US in 2022 was clade IIb, which seems to be diffi
by owenmarshall 2y ago
One important note with mpox is that there are two distinct lineages of the virus at play: the outbreak in the US in 2022 was clade IIb, which seems to be difficult to spread - hence the “close physical contact” attribution. It also had a low observed CFR.
Clade I mpox is the current outbreak under discussion. It spreads far easier - most pathways are likely not sexual contact - and has an observed CFR 10x higher than IIb.
In other words: this is a very different virus than what we saw in 2022.
https://centerforhealthsecurity.org/sites/default/files/2024-06/20240610-mpoxsituationreport.pdf https://centerforhealthsecurity.org/sites/default/files/2024...