2 ms·
For most cases, yes. Antibiotics discovery? Sure, mice are awesome. But mice make really bad models for anything to do with brain, aging, inflammation, and can
by cyberax 2y ago
For most cases, yes. Antibiotics discovery? Sure, mice are awesome.
But mice make really bad models for anything to do with brain, aging, inflammation, and cancer. That's why comments "in mice" are appropriate in these areas.
And it's not at all controversial, here are my citations:
https://www.pnas.org/doi/full/10.1073/pnas.1222878110 https://www.pnas.org/doi/full/10.1073/pnas.1222878110
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615039/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615039/
Mice studies are not useless, for sure. But they're almost always are not directly translatable to humans.
- signatoremo 2y agoAs a layman, why should I trust your citation over studies that highlight the advantages of using mice in aging research? - [0] > But mice make really bad models for anything to do with brain, aging, inflammation, and cancer If mice is really bad for research in the fields you mentioned, why do scientists around the world continue to use it? Wouldn’t they know it’s a dead end? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074346/#:~:text=Mice%20are%20an%20ideal%20mammalian,lifespan%20and%20age%2Drelated%20diseases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074346/#:~:tex....