I've seen other data that says that 50% of weight lost on these drugs is muscle mass, which is high for weight loss. You should expect to lose both muscle and f

I've seen other data that says that 50% of weight lost on these drugs is muscle mass, which is high for weight loss. You should expect to lose both muscle and fat when losing weight, but that's a very high ratio. With weight lifting, you can attenuate that a bit, perhaps completely. It would be interesting to see a study that compares people who take GLP-1 drugs and make no other modifications and others who lift heavy weights under supervision. The other issue that should be studied is diet. If you eat a poor diet lacking in protein and then you take drugs to make you less hungry and now you just eat the same diet but less, you may not be getting nearly enough protein. It would also be good to study the impacts of protein consumption while taking these drugs. I also wonder about the velocity of weight loss. Losing weight too fast could also be part of the issue.