4 ms·
Nature article: https://www.nature.com/articles/s41586-024-07767-5 https://www.nature.com/articles/s41586-024-07767-5 >> Therapeutic targeting of this neuro–ca
by adamredwoods 2y ago
Nature article: https://www.nature.com/articles/s41586-024-07767-5 https://www.nature.com/articles/s41586-024-07767-5
>> Therapeutic targeting of this neuro–cancer axis with the TACR1 antagonist aprepitant, an approved anti-nausea drug, suppressed breast cancer growth and metastasis in multiple models. Our findings reveal that tumour-induced hyperactivation of sensory neurons regulates multiple aspects of metastatic progression in breast cancer through a therapeutically targetable neuropeptide/extracellular ssRNA sensing axis.
Does anyone know of any clinical trials?
- adamredwoods 2y agoNow featured in Nature newsletter: https://www.nature.com/articles/d41586-024-02555-7 https://www.nature.com/articles/d41586-024-02555-7