If it was a device I was actually making I'd put in really itchy micro-tendrils that pierce the skin, but in Dune there's plot reasons it has to be dramatic, an

If it was a device I was actually making I'd put in really itchy micro-tendrils that pierce the skin, but in Dune there's plot reasons it has to be dramatic, and anyway "I survived the itchy box" is way less cool than "I survived the pain box".