The easiest thing to do is to probably just drag the hyperlink into the right window manually. Or maybe you can script it at the OS shortcut level, making a UR

The easiest thing to do is to probably just drag the hyperlink into the right window manually. Or maybe you can script it at the OS shortcut level, making a URL handler script that captures all https links and then does a regex on them to decide which Chrome profile to launch. Note that the Chrome command-line to open a specific profile seems to change every so often, so not sure which of these is current, but hopefully one of them still works... https://superuser.com/questions/377186/how-do-i-start-chrome-using-a-specified-user-profile https://superuser.com/questions/377186/how-do-i-start-chrome...