3 ms·

'smart' insulin that responds to changing blood sugar levels in real time

28 points by sorokod 2y ago

paulcole 2y ago
> People with type 1 diabetes may in future only need to give themselves insulin once a week, say experts Whenever an article about T1D includes mention of an uncertain and unspecified future date, it’s relatively safe to replace it with “never.” As someone with T1D, I won’t be holding my breath waiting for this. Personally I’m quite satisfied with multiple daily injections.
- stranded22 2y ago
  Yes - my wife said when she was diagnosed, she was told to keep the faith as there would probably be a cure in 5 years. That was 34 years ago.
  - thrownv7032g 2y ago
    Which is a wonderful improvement since the 60s when kids were told they'd die horribly by 40!
    - stranded22 2y ago
      Yes - she was very upset when she was told she'd get a certificate if she lives for another 50 years (not the best thing to say to an 11 year old). She REALLY didn't think she'd live to 40. The technology has greatly improved - her closed loop pump has been life changing. Not a cure though and things still go wrong. So - when things are tough, they are very tough but thankfully there are fewer of those days now.
bluesounddirect 2y ago
So my wife is a t1d for the last 36 years. The work we both believe in is a biological cure. I.e. identify the pathogen that triggers t1d developing a vaccine . As well as finding a cure for the people who are already sick. There is almost no incentive for any pharmaceutical company to pursue this , T1D drugs make them gobs of cash.
- pkaye 2y ago
  Isn't the claim most of the medical research is funded by governments so they should have control of what should be prioritized?
- rcxdude 2y ago
  Is there much plausibility of such a cure? The problem is autoimmune AFAIK (maybe triggered by an infection), and once it happens the relevant cells are dead and it'd take both regrowing them and immunotherapy.
andrewjl 2y ago
How does this compare to something like donislecel[1][2]? [1]: https://en.wikipedia.org/wiki/Donislecel https://en.wikipedia.org/wiki/Donislecel [2]: https://www.fda.gov/vaccines-blood-biologics/lantidra https://www.fda.gov/vaccines-blood-biologics/lantidra

28 points by sorokod 2y ago

> People with type 1 diabetes may in future only need to give themselves insulin once a week, say experts Whenever an article about T1D includes mention of an uncertain and unspecified future date, it’s relatively safe to replace it with “never.” As someone with T1D, I won’t be holding my breath waiting for this. Personally I’m quite satisfied with multiple daily injections.

stranded22 2y ago
Yes - my wife said when she was diagnosed, she was told to keep the faith as there would probably be a cure in 5 years. That was 34 years ago.
- thrownv7032g 2y ago
  Which is a wonderful improvement since the 60s when kids were told they'd die horribly by 40!
  - stranded22 2y ago
    Yes - she was very upset when she was told she'd get a certificate if she lives for another 50 years (not the best thing to say to an 11 year old). She REALLY didn't think she'd live to 40. The technology has greatly improved - her closed loop pump has been life changing. Not a cure though and things still go wrong. So - when things are tough, they are very tough but thankfully there are fewer of those days now.

bluesounddirect 2y ago

So my wife is a t1d for the last 36 years. The work we both believe in is a biological cure. I.e. identify the pathogen that triggers t1d developing a vaccine . As well as finding a cure for the people who are already sick. There is almost no incentive for any pharmaceutical company to pursue this , T1D drugs make them gobs of cash.

pkaye 2y ago
Isn't the claim most of the medical research is funded by governments so they should have control of what should be prioritized?
rcxdude 2y ago
Is there much plausibility of such a cure? The problem is autoimmune AFAIK (maybe triggered by an infection), and once it happens the relevant cells are dead and it'd take both regrowing them and immunotherapy.

andrewjl 2y ago

How does this compare to something like donislecel[1][2]? [1]: https://en.wikipedia.org/wiki/Donislecel https://en.wikipedia.org/wiki/Donislecel [2]: https://www.fda.gov/vaccines-blood-biologics/lantidra https://www.fda.gov/vaccines-blood-biologics/lantidra