Yes but many people that have had kids get Alzheimer's. AD isnt aggressively selected against because it is only deleterious past reproductive age. It's true b

Yes but many people that have had kids get Alzheimer's. AD isnt aggressively selected against because it is only deleterious past reproductive age. It's true but AD is likely not one disease but is many different mutations causing a family of shared symptoms which makes it hard to study. It's often better to gain a mechanistic understanding in a reductive model because you'd not have the statistical power in a mixed population to see anything at all.