While true, being negative in a semiconductor system is very relevant though because any P-N junction is a diode. So your ability to propagate current (and thus

While true, being negative in a semiconductor system is very relevant though because any P-N junction is a diode. So your ability to propagate current (and thus downstream voltages) does depend on the voltages all pointing the right direction. note: I am aware that strictly speaking a CPU isn't transistors, but it is a lot of variously doped silicon still.