There has been previous observational studies for erythritol, but this was not was not an observational study. It was straight forward experiment. They gave s

There has been previous observational studies for erythritol, but this was not was not an observational study. It was straight forward experiment. They gave small group of people drink with erythritol and observed (P<0.0001) in everyone really big increase in markers for TRAP6 that activates thrombin receptors responsible for the coagulation. erythritol -> coagulation link was direct. When you combine it with observational studies in larger populations. It harder to explain them away with other habits and conditions. >The present studies suggest that following ingestion of an artificially sweetened food harboring typical levels of erythritol as artificial sweetener, plasma levels of erythritol remain elevated for many days, well above the thresholds necessary to enhance stimulus-dependent platelet reactivity, even among healthy volunteers. . .This is of concern given that the very subjects for whom artificial sweeteners are marketed (patients with diabetes, obesity, history of CVD and impaired kidney function) are those typically at higher risk for future CVD events https://www.science.org/content/blog-post/trouble-erythritol https://www.science.org/content/blog-post/trouble-erythritol