Here's [1] a biochemist talking about an erythritol study (didn't check if it's the same one, but it's the same claimed symptom). They controlled for the obviou

Here's [1] a biochemist talking about an erythritol study (didn't check if it's the same one, but it's the same claimed symptom). They controlled for the obvious risk factors (though with the usual caveats that controlling for things is hard), and they have a claimed mechanism of action: > But we seem to have spotted a toxic effect now. This latest paper shows that plasma erythritol levels actually make a good predictor of major cardiovascular trouble (heart attack/MI, stroke, CV-associated deaths). In 1,157 patients volunteers undergoing three-year longitudinal evaluation, the patients in the highest quartile of plasma erythritol concentration were very strong outliers for CV events. That correlation holds up after controlling for all sorts of other dietary and physical variables (weight, age, gender, known cardiovascular risk factors, and more). And on top of that, the authors demonstrate a surprising but extremely plausible explanation for these findings: erythritol, in both in vitro and in vivo assays, enhances platelet aggregation. > ...I myself will be studiously avoiding it from here on until someone can convince me it’s safe. You may feel similarly after looking at the evidence. There are also other studies (same chemist in [2]) claiming the same effect for xylitol, another related sugar alcohol. ----- [1] https://www.science.org/content/blog-post/trouble-erythritol https://www.science.org/content/blog-post/trouble-erythritol [2] https://www.science.org/content/blog-post/and-now-xylitol https://www.science.org/content/blog-post/and-now-xylitol