4 ms·
The ribosome lowers the entropic penalty of protein folding (Nature)
- mjfl 2y agoThere are also specific folding chaperones like HSP60 which is basically a barrel which isolates a newly translated protein from the rest of the cell so that it can fold properly, and then pops open to release it! https://en.wikipedia.org/wiki/Chaperonin https://en.wikipedia.org/wiki/Chaperonin
- gradschoolfail 2y agoThere are chaperones that bind to the ribosome. Hsp60/70 are found in higher conc near ribosome too.