My mother has Alzheimer’s and I would love to be able to blame her condition and lack of treatment on anyone at all. It would be immensely, primally satisfying

My mother has Alzheimer’s and I would love to be able to blame her condition and lack of treatment on anyone at all. It would be immensely, primally satisfying - which to me is a warning flag for cognitive bias. I think the logical pathway between “two 20 year old papers that ‘sparked’ the Amyloid hypothesis are responsible for the entire research agenda and billions spent on ineffective drugs” is strained. “Sparked” may be true, but the idea that a few twenty-year old fraudulent images tricked Big Pharma into spending two decades chasing this hypothesis and developing drugs, and all along the way the whole thing was based on fake data that nobody every bothered to test in a subsequent experiment? That seems deeply unlikely to me. If true I would like to see that case made with evidence. TL;DR What I am not saying: fraud is acceptable. What I am saying is that there are many replication and error correction systems in science, and people with an axe to grind really don’t want to understand that.