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True. and the quality of the genome assemblies is getting far better thanks to sequencing technologies that can easily generate data for 200,000 consecutive bas
by robwwilliams 2y ago
True. and the quality of the genome assemblies is getting far better thanks to sequencing technologies that can easily generate data for 200,000 consecutive basepairs.
But just to circle back on junk DNA—-most of it is non-functional baggage—-the result of our constant battles with viruses and replication errors.
- NFVLCP 2y agoPerhaps at least some of that "non-functional" DNA is so only after the completion of our nanotechnological self-assembly process, which is surely somewhat complex.
- Qem 2y ago> But just to circle back on junk DNA—-most of it is non-functional baggage—-the result of our constant battles with viruses and replication errors. So, like the middle managers for the genome.
- tetris11 2y agobut their preservation/conservation lends credence to their (as of yet still unknown) utility
- amy-petrik-214 2y agomeh a lot of the mega size genome have been well known. i can think of ameoba at 200x more genome than human and a gorillion polyploid plants. Some have this has been known the last 20-30 years. Some further back. Anyone can look at some chromosomes in a microscope, no sequencing, can say if something is polyploid or not. It's a whole field, called cytobanding. Now as far as assemblies what is interesting there, we never sequencing the human genome . What we did was sequence a lot of the human genome "except for the hard parts, seems impossible". Well in the past few years the T2T projects has successfully sequenced the whole dang thing. Just because something is "hard" or "more repetitive" don't mean ain't nothing interdasting in dere.