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Notably I started Adderall this year and so far I’ve lost 20 pounds. I’m surprised everyone is so excited about Ozempic when other drugs can give similar result

Notably I started Adderall this year and so far I’ve lost 20 pounds. I’m surprised everyone is so excited about Ozempic when other drugs can give similar results. I don’t even take a huge dose, just 10mg XR, but it seems to keep my appetite in check.

KeyBoardG 2y ago
Well its an amphetamine, so there's that.
llamaimperative 2y ago
Are you actually surprised or is this just a turn of phrase? Because there are very good, fairly obvious reasons to prefer Ozempic over an amphetamine for weight loss.
- touisteur 2y ago
  Isn't it part of the plot of Requiem for a Dream ?
  - qwerty456127 2y ago
    Which obviously is dramatically exaggerated because it literally is a drama and a masterpiece of propaganda. Although I don't recommend trying it at home without supervision of a competent doctor and believe there are numerous people to whom it did more harm than good, I still am sure there are many people sustainably taking amphetamines (some even black market) for no harm at all and for great good managing their ADHD and appetite successfully.
    - touisteur 2y ago
      Yes of course. Although my two DTs and tapering off the bottle gave me a new appreciation to this movie. Reality can be far worse than Aronofsky's worst.
  - swader999 2y ago
    Flowers for Algernon.
  - FooBarBizBazz 2y ago
    Beat me to it. That movie hits like a ton of bricks.
- TaylorAlexander 2y ago
  Well in my case, it turns out the benefits of adderall are extremely helpful. I can’t imagine I’m the only one who at 39 years old still had never tried adderall and also struggled with weight loss, who finds the combination of effects beneficial. Meanwhile when I consider ozempic myself instead, I’d get the weight loss but not the focus benefit I’ve sorely needed. I am really not the type to seek a “weight loss drug” so I don’t know the state of mind of those who do (big fan of the Maintenance Phase podcast!), it just seems to me if people want focus and weight loss at the same time they might want to consider it. I see some “it’s an amphetamine” like that means it’s obviously bad. But I guess we all know that “glucagon-like peptide-1 receptor agonists” are totally fine, sure. I think I would posit that amphetamines are more well understood, but I’m no expert. Certainly I could have realized it would lead to weight loss, I just never really thought of it that way. I can’t be the only one, and I am simply surprised it’s not a part of the broader conversation.
  - gwbas1c 2y ago
    > Certainly I could have realized it would lead to weight loss, I just never really thought of it that way. I can’t be the only one, and I am simply surprised it’s not a part of the broader conversation. Here's the thing... Unless you (err, uhm) need an amphetamine, they really have nasty side effects and can lead to serious health problems. IE, in the 1960s and 1970s they were used for weight loss, and they were pulled from the market for good reason. You can go do the digging needed to find out why, but the cliff notes reason is that amphetamines increase risk of heart attack, and for many people cause amphetamine psychosis when used for extended periods of time.
    - samstave 2y ago
      + @TaylorAlexander You'll both love this Joe Rogan Guest: https://www.youtube.com/watch?v=yUsJIcqwARk https://www.youtube.com/watch?v=yUsJIcqwARk >>Norman Ohler is an author and screenwriter whose books include "Blitzed: Drugs in Nazi Germany," "The Bohemians: The Lovers Who Led Germany's Resistance Against the Nazis," and "Tripped: Nazi Germany, The CIA and the Dawn of the Psychedelic Age." He talks a lot about the history of the making of and marketing and use of meth from its discovery and used by nazis, military, cia, etc... Its fantasic.
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renewiltord 2y ago
Yeah, that's normal. Phentermine was a commonly prescribed weight-loss amphetamine before the GLP-1 boys showed up. You will also get these effects with caffeine and cocaine.
- Analemma_ 2y ago
  I was on phentermine for weight loss before switching to semaglutide. I found the former would suppress my appetite well for several months, and then the effect vanished as tolerance built. If the parent commenter is finding that amphetamines work indefinitely for appetite suppression, great, but they often do not.
  - mrguyorama 2y ago
    For ADHD people, some of the weight loss from Adderal comes from reduced ADHD symptoms, like reduced dopamine seeking, so you stop mindlessly eating whole bags of chips, and reduced self medication with other drugs like weed and alcohol
    - qwerty456127 2y ago
      Great point.
gwbas1c 2y ago
Adderall is just a reformulated weight loss drug: https://en.wikipedia.org/wiki/Adderall#History https://en.wikipedia.org/wiki/Adderall#History > The pharmaceutical company Rexar reformulated their popular weight loss drug Obetrol following its mandatory withdrawal from the market in 1973 > In 1994, Richwood Pharmaceuticals acquired Rexar and began promoting Obetrol as a treatment for ADHD It's worth reading https://en.wikipedia.org/wiki/Obetrol https://en.wikipedia.org/wiki/Obetrol to understand why it isn't promoted for weight loss. In general, amphetamines are easily abused and can lead to long term health problems.
astrange 2y ago
It doesn't work that way for most people afaik, but also Ozempic isn't a controlled substance or illegal for tourists to bring into other countries like Adderall.

KeyBoardG 2y ago

Well its an amphetamine, so there's that.

llamaimperative 2y ago

Are you actually surprised or is this just a turn of phrase? Because there are very good, fairly obvious reasons to prefer Ozempic over an amphetamine for weight loss.

touisteur 2y ago
Isn't it part of the plot of Requiem for a Dream ?
- qwerty456127 2y ago
  Which obviously is dramatically exaggerated because it literally is a drama and a masterpiece of propaganda. Although I don't recommend trying it at home without supervision of a competent doctor and believe there are numerous people to whom it did more harm than good, I still am sure there are many people sustainably taking amphetamines (some even black market) for no harm at all and for great good managing their ADHD and appetite successfully.
  - touisteur 2y ago
    Yes of course. Although my two DTs and tapering off the bottle gave me a new appreciation to this movie. Reality can be far worse than Aronofsky's worst.
- swader999 2y ago
  Flowers for Algernon.
- FooBarBizBazz 2y ago
  Beat me to it. That movie hits like a ton of bricks.
TaylorAlexander 2y ago
Well in my case, it turns out the benefits of adderall are extremely helpful. I can’t imagine I’m the only one who at 39 years old still had never tried adderall and also struggled with weight loss, who finds the combination of effects beneficial. Meanwhile when I consider ozempic myself instead, I’d get the weight loss but not the focus benefit I’ve sorely needed. I am really not the type to seek a “weight loss drug” so I don’t know the state of mind of those who do (big fan of the Maintenance Phase podcast!), it just seems to me if people want focus and weight loss at the same time they might want to consider it. I see some “it’s an amphetamine” like that means it’s obviously bad. But I guess we all know that “glucagon-like peptide-1 receptor agonists” are totally fine, sure. I think I would posit that amphetamines are more well understood, but I’m no expert. Certainly I could have realized it would lead to weight loss, I just never really thought of it that way. I can’t be the only one, and I am simply surprised it’s not a part of the broader conversation.
- gwbas1c 2y ago
  > Certainly I could have realized it would lead to weight loss, I just never really thought of it that way. I can’t be the only one, and I am simply surprised it’s not a part of the broader conversation. Here's the thing... Unless you (err, uhm) need an amphetamine, they really have nasty side effects and can lead to serious health problems. IE, in the 1960s and 1970s they were used for weight loss, and they were pulled from the market for good reason. You can go do the digging needed to find out why, but the cliff notes reason is that amphetamines increase risk of heart attack, and for many people cause amphetamine psychosis when used for extended periods of time.
  - samstave 2y ago
    + @TaylorAlexander You'll both love this Joe Rogan Guest: https://www.youtube.com/watch?v=yUsJIcqwARk https://www.youtube.com/watch?v=yUsJIcqwARk >>Norman Ohler is an author and screenwriter whose books include "Blitzed: Drugs in Nazi Germany," "The Bohemians: The Lovers Who Led Germany's Resistance Against the Nazis," and "Tripped: Nazi Germany, The CIA and the Dawn of the Psychedelic Age." He talks a lot about the history of the making of and marketing and use of meth from its discovery and used by nazis, military, cia, etc... Its fantasic.
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renewiltord 2y ago

Yeah, that's normal. Phentermine was a commonly prescribed weight-loss amphetamine before the GLP-1 boys showed up. You will also get these effects with caffeine and cocaine.

Analemma_ 2y ago
I was on phentermine for weight loss before switching to semaglutide. I found the former would suppress my appetite well for several months, and then the effect vanished as tolerance built. If the parent commenter is finding that amphetamines work indefinitely for appetite suppression, great, but they often do not.
- mrguyorama 2y ago
  For ADHD people, some of the weight loss from Adderal comes from reduced ADHD symptoms, like reduced dopamine seeking, so you stop mindlessly eating whole bags of chips, and reduced self medication with other drugs like weed and alcohol
  - qwerty456127 2y ago
    Great point.

gwbas1c 2y ago

Adderall is just a reformulated weight loss drug: https://en.wikipedia.org/wiki/Adderall#History https://en.wikipedia.org/wiki/Adderall#History > The pharmaceutical company Rexar reformulated their popular weight loss drug Obetrol following its mandatory withdrawal from the market in 1973 > In 1994, Richwood Pharmaceuticals acquired Rexar and began promoting Obetrol as a treatment for ADHD It's worth reading https://en.wikipedia.org/wiki/Obetrol https://en.wikipedia.org/wiki/Obetrol to understand why it isn't promoted for weight loss. In general, amphetamines are easily abused and can lead to long term health problems.

astrange 2y ago

It doesn't work that way for most people afaik, but also Ozempic isn't a controlled substance or illegal for tourists to bring into other countries like Adderall.