> The biggest push-back from the medical profession is diagnosing cancers that are not clinically relevant and treatable [...]. There is also a cost benefit dyn

> The biggest push-back from the medical profession is diagnosing cancers that are not clinically relevant and treatable [...]. There is also a cost benefit dynamic of increasing preventative screening, for example lowering the prescribed age for breast screening would save lives but may carry costs for nations or corporations that are unacceptable. One major driver in not screening for everything that can be screened for is the base rate fallacy [1]: We usually screen for things that are rare in the general population and in that case a large fraction of positive tests are false positives. But each positive test has to be followed up and potentially causes harm (because of invasive biopsies, psychological burden etc.). [1] https://en.m.wikipedia.org/wiki/Base_rate_fallacy https://en.m.wikipedia.org/wiki/Base_rate_fallacy