Not vanillaos, but bluefin/silverblue. You can manage many user level programs via toolbox or distrobox in a similiar way as a regular distro, but the packages

Not vanillaos, but bluefin/silverblue. You can manage many user level programs via toolbox or distrobox in a similiar way as a regular distro, but the packages are installed in your $HOME. You can still use regular containers as well too. Although you can still add extra system level stuff if you desire via layering (or soon via systemd sysext)