That's always the problem with these things. You can no longer leverage the bigger ecosystem (e.g. just copy HTML templates from libraries), and I can probably

That's always the problem with these things. You can no longer leverage the bigger ecosystem (e.g. just copy HTML templates from libraries), and I can probably count on no fingers the number of decent designers I've met who knew python. So as soon as you want to grow your team you'll end up with a split. Still, for projects that are only likely to stay small it might be fun. But then you'll have to remember how it works after coming back from your day job that uses a more mainstream framework.