5 ms·

I wouldn't be surprised if the lack of pressure fluctuations would cause harm in the long run (although this isn't meant for the long run). Hearts have been be

I wouldn't be surprised if the lack of pressure fluctuations would cause harm in the long run (although this isn't meant for the long run). Hearts have been beating for a very, very long time, and I'm sure other biological structures have taken advantage of that.

HPsquared 2y ago
I wonder if they prescribe something like walking or jogging as a substitute "repetitive movement" to get things moving.
iancmceachern 2y ago
This is a whole thing. Look up "pump head". Also check out: https://ventriflo.com/ https://ventriflo.com/
jnurmine 2y ago
As I've understood it, not having a pulse creates all kinds of problems, blood clots and whatnot. It's simply not good for the blood, nor the blood flow. The body isn't made for it. Pulsatile flow doesn't have such issues, so a Swedish company called Real Heart is making a TAH that pulses like a heart. So far they've done successful tests with sheep and tons of testing of various blood parameters which look way better than traditional continuous-flow TAHs. Clinical trials on humans should be coming up relatively soon. I hope they make it, and can improve it and make it smaller to fit children etc. It's pretty interesting technology.
- alan-hn 2y ago
  Here is one from Carmat that is already in use in Europe https://www.carmatsa.com/en/our_product/ https://www.carmatsa.com/en/our_product/
- rediguanayum 2y ago
  Here's a video where Bivacor is working on making their impeller design simulate a pulse: https://youtu.be/3uV8XZcIBbk?si=I9Gf6pEd9v71Q7JJ https://youtu.be/3uV8XZcIBbk?si=I9Gf6pEd9v71Q7JJ. Also has nice interview with the inventor/founder Daniel Timms where he talks about the motivation for doing this companany i.e. when his dad got heart failure.
- kaba0 2y ago
  I’m sure it does cause some problems as the human body is very intricate, but in the capillaries blood flow is often approximated as a steady flow in medical science.

HPsquared 2y ago

I wonder if they prescribe something like walking or jogging as a substitute "repetitive movement" to get things moving.

iancmceachern 2y ago

This is a whole thing. Look up "pump head". Also check out: https://ventriflo.com/ https://ventriflo.com/

jnurmine 2y ago

As I've understood it, not having a pulse creates all kinds of problems, blood clots and whatnot. It's simply not good for the blood, nor the blood flow. The body isn't made for it. Pulsatile flow doesn't have such issues, so a Swedish company called Real Heart is making a TAH that pulses like a heart. So far they've done successful tests with sheep and tons of testing of various blood parameters which look way better than traditional continuous-flow TAHs. Clinical trials on humans should be coming up relatively soon. I hope they make it, and can improve it and make it smaller to fit children etc. It's pretty interesting technology.

alan-hn 2y ago
Here is one from Carmat that is already in use in Europe https://www.carmatsa.com/en/our_product/ https://www.carmatsa.com/en/our_product/
rediguanayum 2y ago
Here's a video where Bivacor is working on making their impeller design simulate a pulse: https://youtu.be/3uV8XZcIBbk?si=I9Gf6pEd9v71Q7JJ https://youtu.be/3uV8XZcIBbk?si=I9Gf6pEd9v71Q7JJ. Also has nice interview with the inventor/founder Daniel Timms where he talks about the motivation for doing this companany i.e. when his dad got heart failure.
kaba0 2y ago
I’m sure it does cause some problems as the human body is very intricate, but in the capillaries blood flow is often approximated as a steady flow in medical science.