3 ms·

Couldn't make much sense of the results =). You should add a snippit to the wikipedia page http://en.wikipedia.org/wiki/IPSP http://en.wikipedia.org/wiki/IPSP

• davi 18y ago
  You're right, that was a pretty crummy suggestion. I looked at the wikipedia IPSP page and didn't like it much, either. A little deeper googling gave me this: http://icwww.epfl.ch/~gerstner/SPNM/node15.html#SECTION02133100000000000000 http://icwww.epfl.ch/~gerstner/SPNM/node15.html#SECTION02133... To help parse figure 2.12: 'Resting potential' = voltage between inside and outside of the neuron in the absence of any excitatory or inhibitory input. It is generated constitutively by ion pumps in the cell. When cell receives inhibitory input, its voltage drops and it become 'hyperpolarized'. This causes a certain type of calcium ion channel, the 'T-type', to gain the capability of opening (it stops being 'inactivated'). When the inhibitory input ceases, the cell's constitutive ion pumps return it to its resting potential. As the voltage of the cell increases, some T-type channels begin to open, leading to an influx of calcium ions (there are more calcium ions outside the cell than inside), which in turn leads to the cell's voltage to increase further. Now the cell's voltage shoots above its resting potential, and voltage-dependent sodium channels begin to open. Sodium ions rush in, and a spike is generated. And the payoff to me for trying to a little bit better job of answering your question is that I discovered what looks to be a pretty good resource: http://icwww.epfl.ch/~gerstner/SPNM/SPNM.html http://icwww.epfl.ch/~gerstner/SPNM/SPNM.html