5 ms·

Absolutely that’s why substance abuse is very dangerous. I would even append permanent destruction of receptors to the list.

• LoganDark 2y ago
  Oh, right; I forgot that's also a thing. I try to advocate for the reduction of SSRI use for that reason. It's a known side effect that they can permanently destroy or desensitize serotonin receptors when used for periods that exceed around a year or two (this varies by individual). I wouldn't even go that far, personally, but some people's doctors do not know about that effect of SSRIs and keep prescribing them for five years or more, in which case I usually take it upon myself to educate the person directly if their doctor does not know. I don't tell them to stop taking it immediately or anything, just that they might want to watch how long they stay on it. (Side note: I don't know what's so special about prescribers when most of them don't even fully understand the substances they're prescribing. It's possible that fully educating myself about what I'm doing might actually have been better than having blindly accepted a prescription for it, at least in some hypothetical future where this stuff can even be prescribed at all. I guess some people associate illegality automatically with immorality/irresponsibility.)