OR-Tools has a lot of bindings in different languages, though Javascript/Node doesn't seem to be a first-class supported environment. Looks like https://www.npm

OR-Tools has a lot of bindings in different languages, though Javascript/Node doesn't seem to be a first-class supported environment. Looks like https://www.npmjs.com/package/node_or_tools https://www.npmjs.com/package/node_or_tools ports a few solver packages into Node so if those solvers fit your needs you can use this package.