4 ms·
>Healthy adults were tracked before, during and for 3 weeks after high-dose psilocybin (25 mg) and methylphenidate (40 mg), and brought back for an additional p
by lawlessone 2y ago
>Healthy adults were tracked before, during and for 3 weeks after high-dose psilocybin (25 mg) and methylphenidate (40 mg), and brought back for an additional psilocybin dose 6–12 months later.
Not simultaneously I hope.. that sounds like it would be a rough ride
- jkingsman 2y agoNo, they were separate dosages to compare FC effects.
- titanomachy 2y ago"[methylphenidate] was selected as the active control condition to simulate the cardiovascular effects and physiological arousal (that is, controlling for dopaminergic effects) associated with psylocybin"
- brotchie 2y ago"it can generally be assumed that there is approximately 15 mg (+/- 5 mg) of psilocybin per gram of dried mushroom" -Wikipedia So 25mg is ~1.5g of dried mushrooms. Decent dose, but not a "omg I'm one with the universe." For instance, a "Hero Dose" typically starts at 5g of dried mushrooms, so ~3x the dosage used in the study. Though it's possible the uptake rate using their dosing mechanism is much higher than "stomach acid digested dried mushrooms."
- mistrial9 2y agosome kinds of mushrooms can grow tolerance fairly quickly, also.. based on info from a friend
- newzisforsukas 2y ago> So 25mg is ~1.5g of dried mushrooms. 1.25g - 2.5g *
- collyw 2y agoThat isn't a high dose. Medium.