I'm not in biology/medicine, but my impression is inflammation is mostly about fighting off infectious diseases. Which, historically, have been a leading kille

I'm not in biology/medicine, but my impression is inflammation is mostly about fighting off infectious diseases. Which, historically, have been a leading killer of mammals. If current conditions (whether for lab mice, or humans) have removed ~99% of the deadly diseases from the equation - then it's kinda like someone who's heterozygous for sickle cell being stuck in a malaria-free region.