3 ms·
mRNA vaccines need a target, and if there is a target, there are several approaches that already do this (anti-body drug conjugates), and sometimes work, someti
by adamredwoods 2y ago
mRNA vaccines need a target, and if there is a target, there are several approaches that already do this (anti-body drug conjugates), and sometimes work, sometimes doesn't.
I don't think anybody thinks it "didn't work out". It's still actively ongoing:
https://www.mdanderson.org/newsroom/md-anderson-curevac-enter-strategic-collaboration-develop-novel-cancer-vaccines.h00-159696756.html https://www.mdanderson.org/newsroom/md-anderson-curevac-ente...
https://investors.modernatx.com/news/news-details/2023/Moderna-and-Merck-Announce-mRNA-4157V940-an-Investigational-Personalized-mRNA-Cancer-Vaccine-in-Combination-With-KEYTRUDAR-pembrolizumab-was-Granted-Breakthrough-Therapy-Designation-by-the-FDA-for-Adjuvant-Treatment-of-Patients-With-High-Risk-Melanom/default.aspx https://investors.modernatx.com/news/news-details/2023/Moder...
(from 2021):
https://link.springer.com/article/10.1186/s12943-021-01348-0/tables/1 https://link.springer.com/article/10.1186/s12943-021-01348-0...
https://link.springer.com/article/10.1186/s12943-021-01348-0 https://link.springer.com/article/10.1186/s12943-021-01348-0