3 ms·

Nanorobot with hidden weapon kills cancer cells

20 points by gmays 2y ago

deleted 2y ago
[deleted]
westurner 2y ago
Looks like gold nanoparticles kill glioblastoma colon cancer: https://news.ycombinator.com/item?id=40819864 https://news.ycombinator.com/item?id=40819864 : >> He emphasizes, "Any scientist can already use our model at the design stage of their own research to instantly narrow down the number of nanoparticle variants requiring experimental verification." >> "Modeling Absorption Dynamics of Differently Shaped Gold Glioblastoma and Colon Cells Based on Refractive Index Distribution in Holotomographic Imaging" (2024) https://onlinelibrary.wiley.com/doi/10.1002/smll.202400778 https://onlinelibrary.wiley.com/doi/10.1002/smll.202400778 > Holotomography: https://en.wikipedia.org/wiki/Holotomography https://en.wikipedia.org/wiki/Holotomography >>> Could part of the cancer-killing [200nm nanoparticle gold stars] be more magnetic than Gold (Au), for targeting treatment? Magnets, nano robots, NIRS targeting, "Whole-body magnetic resonance imaging at 0.05 Tesla" [1800W] https://www.science.org/doi/10.1126/science.adm7168 https://www.science.org/doi/10.1126/science.adm7168 .. https://news.ycombinator.com/item?id=40335170 https://news.ycombinator.com/item?id=40335170
westurner 2y ago
Article: ”A DNA Robotic Switch with Regulated Autonomous Display of Cytotoxic Ligand Nanopatterns” (2024) https://www.nature.com/articles/s41565-024-01676-4 https://www.nature.com/articles/s41565-024-01676-4
roenxi 2y ago
It relies on acid? Try https://en.wikipedia.org/wiki/Helicobacter_pylori https://en.wikipedia.org/wiki/Helicobacter_pylori too, please. In the long term I expect engineering to outperform evolution in the same way that mathematics allowed humans to establish such a practical lead that we're almost in a different class to animals. It'll be interesting to see how quickly and how lopsided the advantage is over cells if nanorobots take off.
- jjtheblunt 2y ago
  Molecular organic biology _is_ already since the dawn of time the realization of nanobots through enzymes and various automata built in chemistry. I think (to your point) what is interesting is adding new chemical nanobot-esque compounds that nature had not yet developed. For example that can coordinate with external focused energy.
- eddiewithzato 2y ago
  evolution allowed this to happen, basically it’s evolution all the way down ;)
_nalply 2y ago
Not an expert but it seems acid is not specific enough. There are acidic organs like the stomach but also the vagina. I wonder if the nano robots would then attack stomach and vagina cells. This said, I am pleasantly surprised that nano robots, a scifi idea, are actively researched and tested. As a child I watched a French TV scifi animation series which showed people and their vessel minified and injected into a human body. Now finally it seems this future has started? I hope it is a good start.
- Doxin 2y ago
  As I understand it stomach cells aren't really acid-resistant. The stomach creates mucus to keep the acid from touching the cells.

20 points by gmays 2y ago

deleted 2y ago

[deleted]

Looks like gold nanoparticles kill glioblastoma colon cancer: https://news.ycombinator.com/item?id=40819864 https://news.ycombinator.com/item?id=40819864 : >> He emphasizes, "Any scientist can already use our model at the design stage of their own research to instantly narrow down the number of nanoparticle variants requiring experimental verification." >> "Modeling Absorption Dynamics of Differently Shaped Gold Glioblastoma and Colon Cells Based on Refractive Index Distribution in Holotomographic Imaging" (2024) https://onlinelibrary.wiley.com/doi/10.1002/smll.202400778 https://onlinelibrary.wiley.com/doi/10.1002/smll.202400778 > Holotomography: https://en.wikipedia.org/wiki/Holotomography https://en.wikipedia.org/wiki/Holotomography >>> Could part of the cancer-killing [200nm nanoparticle gold stars] be more magnetic than Gold (Au), for targeting treatment? Magnets, nano robots, NIRS targeting, "Whole-body magnetic resonance imaging at 0.05 Tesla" [1800W] https://www.science.org/doi/10.1126/science.adm7168 https://www.science.org/doi/10.1126/science.adm7168 .. https://news.ycombinator.com/item?id=40335170 https://news.ycombinator.com/item?id=40335170

westurner 2y ago

Article: ”A DNA Robotic Switch with Regulated Autonomous Display of Cytotoxic Ligand Nanopatterns” (2024) https://www.nature.com/articles/s41565-024-01676-4 https://www.nature.com/articles/s41565-024-01676-4

roenxi 2y ago

It relies on acid? Try https://en.wikipedia.org/wiki/Helicobacter_pylori https://en.wikipedia.org/wiki/Helicobacter_pylori too, please. In the long term I expect engineering to outperform evolution in the same way that mathematics allowed humans to establish such a practical lead that we're almost in a different class to animals. It'll be interesting to see how quickly and how lopsided the advantage is over cells if nanorobots take off.

jjtheblunt 2y ago
Molecular organic biology _is_ already since the dawn of time the realization of nanobots through enzymes and various automata built in chemistry. I think (to your point) what is interesting is adding new chemical nanobot-esque compounds that nature had not yet developed. For example that can coordinate with external focused energy.
eddiewithzato 2y ago
evolution allowed this to happen, basically it’s evolution all the way down ;)

_nalply 2y ago

Not an expert but it seems acid is not specific enough. There are acidic organs like the stomach but also the vagina. I wonder if the nano robots would then attack stomach and vagina cells. This said, I am pleasantly surprised that nano robots, a scifi idea, are actively researched and tested. As a child I watched a French TV scifi animation series which showed people and their vessel minified and injected into a human body. Now finally it seems this future has started? I hope it is a good start.

Doxin 2y ago
As I understand it stomach cells aren't really acid-resistant. The stomach creates mucus to keep the acid from touching the cells.