3 ms·
First cell-free system in which genetic information and metabolism work together
- Jimmc414 2y agohttps://www.science.org/doi/10.1126/science.adn3856 https://www.science.org/doi/10.1126/science.adn3856 "combines in vitro transcription-translation (TX-TL) with a carbon fixation cycle called CETCH (Crotonyl-CoA/Ethylmalonyl-CoA/Hydroxybutyryl-CoA)" They linked a metabolic pathway that converts CO2 into organic molecules ie CETCH with a TX-TL system that can synthesize proteins. The system can partially self-regenerate by producing missing enzymes needed for the CETCH cycle.