3 ms·
... In mice.. And human! cells. From the paper: • Multi-omic analysis of maturation and aging across >45 mouse and human cell types • Common transcription fa
by tomrod 2y ago
... In mice.. And human! cells.
From the paper:
• Multi-omic analysis of maturation and aging across >45 mouse and human cell types
• Common transcription factor pattern for chromatin remodeling in maturation and aging
• Encoded via relative abundance of AP-1, CTCF, and cell identity factor binding sites
• Remodeling mechanism activated by AP-1, stress, systemic factor, or PRC2 inhibition