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> Another is that common fruits like pears, apples, and citrus contain drug like chemicals that alter the metabolism. This is super potent in grapefruit and has
by KennyBlanken 2y ago
> Another is that common fruits like pears, apples, and citrus contain drug like chemicals that alter the metabolism. This is super potent in grapefruit and has been known to cause fatal drug interactions in people on prescribed medicine.
Grapefruit does not "alter the metabolism." Furanocoumarin binds to a receptor in the gut which causes some medications to pass through the gut much faster than normal which affects the level of the medicine in the blood.
That has nothing to do with "metabolism."
It also only affects some medications.
You might want to refrain from commenting on medicine until you have an actual science-based education in it.
- fabian2k 2y agoGrapefruit contains compounds that inhibit Cytochrome P450 and this will affect how various drugs will be metabolized. That is a very direct effect on metabolism and will affect a variety of drugs, but certainly not all of them.
- pfdietz 2y agoThat's not the only mechanism (see other response also). https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions#Mechanism https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_intera...
- guerrilla 2y ago> Grapefruit does not "alter the metabolism." Wrong. https://en.wikipedia.org/wiki/Cytochrome_P450 https://en.wikipedia.org/wiki/Cytochrome_P450