This is probably not exhaustive but I think these frameworks can support HTTP/3 today: - The standard grpc library for C#, dotnet-grpc - It may already be pos

This is probably not exhaustive but I think these frameworks can support HTTP/3 today: - The standard grpc library for C#, dotnet-grpc - It may already be possible in rust with Tonic with the Hyper http transport - It's possible in Go if you use ConnectRPC with quic-go - This is untested but I believe many gRPC-Web implementations in the browser might "just work" with HTTP/3 as well as long as the browsers are informed of the support via the "ALT-SVC" header and the servers supports it.