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I could not find their definition of a high-fat diet. Anecdotally I have often heard researchers of ketogenic diets complain that in animal studies "high-fat di
by david-gpu 2y ago
I could not find their definition of a high-fat diet. Anecdotally I have often heard researchers of ketogenic diets complain that in animal studies "high-fat diets" typically contain high amounts of sugar as well, and thus do not induce a low-insulin state as we see in ketogenic diets.
- guntars 2y agoFrom memory, the study I linked used 40ish percent fat as the high fat diet, so not keto by any means.
- Modified3019 2y agoOne also needs to be aware of the actual fatty acid profile of the lab feed used. The researchers may not even know (or be aware of the possible differences) until asked to track down what the specific feed was. “Animal fat” that is highly unsaturated because it was from pigs fed polyunsatured seed meal byproduct, is going to have different health effects from the more saturated fat from a ruminant like a cow, which typically resist PUFA accumulation. Even breed and time of year will affect the fatty acid contents, so to be sure you always have to test. In this case, looks like the fat was a crisco (pig lard, maby), coconut oil (highly saturated) and corn oil (highly unsaturated) blend. On a related note, on the labels of food you buy, the types of fat listed can be wildly different from what is actually in the food, simply because there is so much variation it’s not economical to test that much. Food items from smaller producers can also just use a generic label provided by the FDA, rather than actually testing themselves.