Android from Honeycomb on is quite nice with a mouse/keyboard combination, particularly if the "mouse" is really a multitouch touchpad. I use my ASUS Transform

Android from Honeycomb on is quite nice with a mouse/keyboard combination, particularly if the "mouse" is really a multitouch touchpad. I use my ASUS Transformer in that configuration more than I use it in tablet form, and I find that both the hardward keyboard and the touchpad work perfectly fine. The real downside isn't the OS support, but the app selection. There are still far too few apps built assuming that some percentage of the userbase will be using richer-than-touchscreen-only input methods, but this is beginning to slowly change as more full-featured office apps and IDEs are starting to appear.