It’s probably not answering all your questions, but https://manuel.kiessling.net/2021/05/02/tutorial-react-single-page-applications-spa-with-a-serverless-aws-ap

It’s probably not answering all your questions, but https://manuel.kiessling.net/2021/05/02/tutorial-react-single-page-applications-spa-with-a-serverless-aws-api-gateway-and-lambda-and-dynamodb-backend-and-terraform-infrastructure-as-code/ https://manuel.kiessling.net/2021/05/02/tutorial-react-singl... might be worth a read. Also, although not React/Node, the thoughts laid out in https://manuel.kiessling.net/2012/09/28/applying-the-clean-architecture-to-go-applications/ https://manuel.kiessling.net/2012/09/28/applying-the-clean-a... have served me well over the years.