You can, with caveats. You can use Clover [0] to bootstrap from a USB key (or anything else) that then hands off to an NVMe drive. Or you can mod your BIOS [1].

You can, with caveats. You can use Clover [0] to bootstrap from a USB key (or anything else) that then hands off to an NVMe drive. Or you can mod your BIOS [1]. I have personally done this on a Supermicro 9th gen, and it works great. YMMV, especially with Dells or HPs which tend to be far more picky about everything. [0]: https://github.com/CloverHackyColor/CloverBootloader https://github.com/CloverHackyColor/CloverBootloader [1]: https://winraid.level1techs.com/t/howto-get-full-nvme-support-for-all-systems-with-an-ami-uefi-bios/30901 https://winraid.level1techs.com/t/howto-get-full-nvme-suppor...