I've never read the Chinese Suihua cohort study so I'm not going to speculate or comment on it. I think "in the last few generations" is a little speculative.

I've never read the Chinese Suihua cohort study so I'm not going to speculate or comment on it. I think "in the last few generations" is a little speculative. There's strong evidence for epigenetic changes being passed from parents, but going further back the evidence is much weaker. > what issue do you take with the Dutch hunger study It's a really narrow study of a rather genetically homogeneous group picked from a really small geographic area and it has all of the issues of any retrospective study. The outcome could just be random chance. If you look at any small closely related group you're just going to find some sort of weird clustering, even if it varies in that group. If similar epigenetic markers showed up in other populations with similar well documented circumstances it would be stronger.