This is an incredible step forward. I know many chronically ill people, myself included, whose condition degenerated in parallel with gastrointestinal issues, o

This is an incredible step forward. I know many chronically ill people, myself included, whose condition degenerated in parallel with gastrointestinal issues, often precisely after antibiotics. Because it doesn't happen to most people, we as a society tend to underestimate how potentially harmful a course of even a mild antibiotic can be - wiping out a portion of the healthy strains and suppressing much of the rest gives other microbes, sometimes incredibly harmful ones, an excellent opportunity to take over. And sometimes, this sticks with you for years and years, and becomes impossible to root out as the organisms adapt to their new place better. Regrettably, C.Diff is somewhat exceptional in that cure rates of FMT alone are incredible(90%+), while most other microbiome-linked conditions - IBS, Ulcerative Colitis, SIBO, and all kinds of assorted stuff like many cases of chronic fatigue or depression - often get no or very temporary benefit. My own experience with DIY FMT was that I experienced 1-2 days of complete relief(brainfog, depression, anhedonia, mild diarrhea), and 3-4w of feeling much better, before symptoms returned in almost-full-force. Many other people have had even less luck- most actual successes involve comprehensive antibiotic pretreatment to get rid of existing microbes, and many repeat transplants, before the benefits stick. Nonetheless, this is a step in a good direction, and will hopefully open doors to further research for other conditions - far, far too many people are forced to deal with severe illness while doctors shrug and funnel everyone into psychiatry for their "psychosomatic symptoms"