3 ms·

High iron levels are almost never caused by exogenous excess iron but rather the cause is always genetic. Iron absorption is very tightly regulated

• aredox 2y ago
  >High iron levels are almost never caused by exogenous excess iron One of the exceptions is using steel cookware: https://en.m.wikipedia.org/wiki/African_iron_overload https://en.m.wikipedia.org/wiki/African_iron_overload Iron absorption is tightly regulated, but can't be totally stopped, and the body has no way to excrete excess iron outside of the rather slow cycle of blood formation and destruction
  • deleted 2y ago
    [deleted]
  • alan-hn 2y ago
    "The probable cause of African iron overload is the combination of excess iron intake and functional changes in ferroportin.[4][5]" It stops when ferroportin uptake of iron is saturated