I can see that the research makes many organoid samples (4000+) mentioned in the paper. This is good to validate the organoid results are consistent. however,

I can see that the research makes many organoid samples (4000+) mentioned in the paper. This is good to validate the organoid results are consistent. however, then correlating the consistent organoid attributes back to attributes of a small parent sample group is weaker on small sample groups than larger ones. here the parent group is tiny… and the severe ASD sufferers is even smaller (n=2 or 3 by my understanding) great foundational research! but surely larger group sizes are required before correlation is confirmed