4 ms·
How much Xylitol? We need resident researchers of HN to help us analyze the paper. Or basically I’m hoping someone can tell me whether the paper is trustworthy
by m_a_g 2y ago
How much Xylitol? We need resident researchers of HN to help us analyze the paper.
Or basically I’m hoping someone can tell me whether the paper is trustworthy or not so I can continue taking mints in peace.
- Enginerrrd 2y agoJust read the paper. In the 2149 participants, detection in fasting plasma was associated with a hazard ratio of 1.57 It was also shown to enhance clotting at the levels detected in fasting plasma (in 10 people) which provides a potential mechanism to explain the effects observed in the larger group. As for how legit it is... The number of people is significant. My only complaint is they didn't measure xylitol directly, rather they tested for polyol or something.
- dev_tty01 2y agoThanks. That's a substantial ratio. Hazen's group is at the Cleveland clinic and has done a lot of good work so there is something there. Anything on how much Xylitol use is required to get to that risk level?
- zw7 2y agoI believe they confirmed it was xylitol with LC-MS to validate it: > Subsequent stable isotope dilution LC-MS/MS analyses (validation cohort) specific for xylitol (and not its structural isomers) confirmed its association with incident MACE
- kurtextrem 2y ago"xylitol-sweetened (30 g) water, an exposure comparable with a pint of numerous xylitol-sweetened ice creams, a xylitol-sweetened bakery good, or several pieces of xylitol-sweetened candy" (source: https://www.reddit.com/r/science/comments/1d9ql2u/comment/l7g9yup/ https://www.reddit.com/r/science/comments/1d9ql2u/comment/l7...)