4 ms·
If you are a geneticist, you would know genetic correlates. The only causality of AD that I assert is with lifestyle factors and genetic factors, e.g. APOE4, th
by OutOfHere 2y ago
If you are a geneticist, you would know genetic correlates. The only causality of AD that I assert is with lifestyle factors and genetic factors, e.g. APOE4, that govern neuroinflammation, as is strongly established.
- naijaboiler 2y agoplease just shush! you are still misleading people. Where the proof that lifestyle factors are causal and not just associative.
- OutOfHere 2y agoWith regard to lifestyle factors, here is some evidence to get you started: Healthy lifestyle and the risk of Alzheimer dementia (PMC7455318) > Compared to participants with 0 to 1 healthy lifestyle factor, the risk of Alzheimer dementia was 37% lower (pooled HR 0.63, 95% CI 0.47–0.84) in those with 2 to 3 healthy lifestyle factors and 60% lower (pooled HR 0.40, 95% CI 0.28–0.56) in those with 4 to 5 healthy lifestyle factors.
- naijaboiler 2y agothats still not causality. silly.
- catlikesshrimp 2y agoI hear this everyday, unfortunately: "If you really know something about [X], you must agree with my [opinion,unbased statements]" The nerve
- OutOfHere 2y agoIt's not opinion when there is evidence: APOE4 homozygozity represents a distinct genetic form of Alzheimer's disease (PMID: 38710950) > The study concludes that APOE4 homozygotes represent a genetic form of AD Healthy lifestyle and the risk of Alzheimer dementia (PMC7455318) > Compared to participants with 0 to 1 healthy lifestyle factor, the risk of Alzheimer dementia was 37% lower (pooled HR 0.63, 95% CI 0.47–0.84) in those with 2 to 3 healthy lifestyle factors and 60% lower (pooled HR 0.40, 95% CI 0.28–0.56) in those with 4 to 5 healthy lifestyle factors.
- deleted 2y ago[deleted]