3 ms·

I thought we didn’t know the cause of Alzheimer’s when it’s not genetic.

throwaway81523 2y ago
It's not known but among other things there is some evidence that it comes from a viral infection earlier in life. Multiple sclerosis is another thing like that. https://www.science.org/content/article/study-links-viral-infections-alzheimer-s-parkinson-s-many-caveats https://www.science.org/content/article/study-links-viral-in...
- OutOfHere 2y ago
  A healthy immune system will keep most viruses in check, but a metabolic mess ultimately becomes an immunologic mess too, leading to brain disease.
  - yxwvut 2y ago
    The world must be so tidy for you. Who needs actual science when we have your facile hunches?
    - deleted 2y ago
      [deleted]
    - OutOfHere 2y ago
      [flagged]
      - jcrites 2y ago
        Please consider presenting the evidence without the personal swipes, and please consider reviewing the HN Guidelines: https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html > Be kind. Don't be snarky. Converse curiously; don't cross-examine. Edit out swipes. > When disagreeing, please reply to the argument instead of calling names. "That is idiotic; 1 + 1 is 2, not 3" can be shortened to "1 + 1 is 2, not 3." Your comments in this thread would be more constructive without the swipes.
        OutOfHere 2y ago
        It's all well and good for you to discipline me, and I will be happy to edit and abide, but what's not good is you letting others unfairly chew me alive. It's just wrong.
        jcrites 2y ago
        Yes, you're right. Multiple people in the thread needed to be reminded of this. I wrote my comment in reply to you since you seemed to be the most active, and several of your replies were the most recent at the time I was responding.
catlikesshrimp 2y ago
Things to consider: * Alzheimer might not be a disease, but a syndrome. (several diseases that look about the same) * Alzheimer's onset might be multifactorial (like diabetes, unlike Hungtington's) * Everything we know about the pathophysiology of Alzheimer might be wrong. What we believe is right would actually prevent us from making progress. It doesn't help that very loud idiots crave for recognition rather than discovery. "I know that I know nothing" ~Socrates(?)

It's not known but among other things there is some evidence that it comes from a viral infection earlier in life. Multiple sclerosis is another thing like that. https://www.science.org/content/article/study-links-viral-infections-alzheimer-s-parkinson-s-many-caveats https://www.science.org/content/article/study-links-viral-in...

OutOfHere 2y ago
A healthy immune system will keep most viruses in check, but a metabolic mess ultimately becomes an immunologic mess too, leading to brain disease.
- yxwvut 2y ago
  The world must be so tidy for you. Who needs actual science when we have your facile hunches?
  - deleted 2y ago
    [deleted]
  - OutOfHere 2y ago
    [flagged]
    - jcrites 2y ago
      Please consider presenting the evidence without the personal swipes, and please consider reviewing the HN Guidelines: https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html > Be kind. Don't be snarky. Converse curiously; don't cross-examine. Edit out swipes. > When disagreeing, please reply to the argument instead of calling names. "That is idiotic; 1 + 1 is 2, not 3" can be shortened to "1 + 1 is 2, not 3." Your comments in this thread would be more constructive without the swipes.
      - OutOfHere 2y ago
        It's all well and good for you to discipline me, and I will be happy to edit and abide, but what's not good is you letting others unfairly chew me alive. It's just wrong.
        jcrites 2y ago
        Yes, you're right. Multiple people in the thread needed to be reminded of this. I wrote my comment in reply to you since you seemed to be the most active, and several of your replies were the most recent at the time I was responding.

catlikesshrimp 2y ago

Things to consider: * Alzheimer might not be a disease, but a syndrome. (several diseases that look about the same) * Alzheimer's onset might be multifactorial (like diabetes, unlike Hungtington's) * Everything we know about the pathophysiology of Alzheimer might be wrong. What we believe is right would actually prevent us from making progress. It doesn't help that very loud idiots crave for recognition rather than discovery. "I know that I know nothing" ~Socrates(?)