3 ms·
Unfortunately, the story for people who discontinue the drug is less rosey. Many regain some or all of the weight lost; it appears to be a temporary alternative
by zdragnar 2y ago
Unfortunately, the story for people who discontinue the drug is less rosey. Many regain some or all of the weight lost; it appears to be a temporary alternative to stomach surgery.
- toomuchtodo 2y agoTargeted gene therapy is the end goal, versus chronic management. We bug fix the human. Think of this as pharma print statement debugging. In the interim, the drug helps those in need of intervention. https://www.fractyl.com/fractyl-health-demonstrates-significant-improvement-in-glucose-control-and-obesity-inpreclinical-studies-of-its-rejuva-glp-1-based-pancreatic-gene-therapy-glp1-pgtxcompared-to-chronic-semaglutide-at/ https://www.fractyl.com/fractyl-health-demonstrates-signific... https://www.remain1study.com/remain-1-study/ https://www.remain1study.com/remain-1-study/
- suzzer99 2y agoDoes this happen any more often than when people lose weight by other means? I was under the impression that something like 90-95% of people who lose significant weight gain a lot of it back.
- zdragnar 2y agoOther means have fewer side effects and cost insurance companies less, meaning they cost you less. Over-priced temporary fixes should be the choice of last resort, not the first one.
- sunshowers 2y agoThe overpricing is not inherent to the manufacturing of these drugs as far as I understand, it's an artifact of the American healthcare system. You know what else is a temporary fix? Vitamin C for scurvy. Your body does not produce it endogenously. You are already a lifelong patient -- all humans are -- and it just so happens that the medication to treat it is part of your diet.
- sunshowers 2y agoThe story for people who discontinue drugs for hypertension is less rosy too.